Download A Matter of Honor by Jeffrey Archer PDF
By Jeffrey Archer
It sort of feels blameless sufficient. A disgraced British colonel bequeaths a mysterious letter to his merely son. however the second Adam Scott opens the yellowing envelope, he units into movement a perilous chain of occasions that threatens to shake the very foundations of the loose world.
Within days, Adam's lover is brutally murdered and he's operating for his existence in the course of the nice towns of Europe, pursued not just via the KGB, yet by means of the CIA and his personal countrymen to boot. Their universal motive is to kill him earlier than the reality comes out. whereas robust males in smoke-filled rooms plot ever extra creative technique of destroying him, Adam reveals himself betrayed and deserted even by way of these he holds so much dear.
When ultimately he involves comprehend what he's in ownership of, he's much more decided to guard it, for it's greater than an issue of lifestyles and death-it's a question of honor.
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Additional info for A Matter of Honor
This IFN dose was well tolerated without adverse side-effects. The overall survival did not differ significantly between the 2 treatment groups. To meet the dose-dependent concept, 50 pa~ tients with IgA and Bence-Jones myelomas entered a pilot study using high doses of natural alpha-IFN . This study showed that the highest dose tested, 30 x 10 6 U of alphaIFN daily, caused unacceptable adverse reactions. The maximal tolerable dose that could be given with only minor side-effects to most patients was 10 x 10 6 U daily for 7 consecutive days repeated every third week.
The best results have been obtained with a combination of streptozotocin and 5-FU or doxorubicin. 5-2 years (6,8,9). However, only 10-30% of patients with carcinoid tumours show objective responses with the same combination and the responses are of very short duration, with a median of less than 6 months [10-12]. Somatostatin has been shown to inhibit symptoms related to neuroendocrine gut and pancreatic tumours and the long-acting analogue Sandostatin has a beneficial effect on these tumours [13,14].
S. s. s. 05 The Mechanisms of Action and the Role of Alpha Interferon in the Therapy of Myeloma 29 Table 4. Response frequencies (%) of alpha-IFN and chemotherapy for induction treatment of previously untreated multiple myeloma patients Treatment schedule Response rate (%) Mean 95% Confidence limits Reference Montuoro et al.  MP (n=21 ) MP/alpha-IFN (n=16) 71 (50-92) 81 (60-100) MP (n=24) MP/alpha-IFN (n=29) 54 (33-75) 41 (CR 7%) (22-60) MP (n=134) MP/alpha-IFN (n=135) 44 (35-54) 37 (29-45) VBMCP/alpha-IFN (n=54) 80% (CR26%) (69-91 ) Kyle et al.